"Lorena" was first published by H. M. Higgins Brothers of Chicago, in 1857; the Library Of Congress holds a copy printed by J.C Shreiner of Macon, Georgia between 1862 and 1864. It has been published and recorded a number of times since, including a 1950s a cappella arrangement by Ralph Hunter, Robert Shaw and Alice Parker.
Webster and Webster also wrote an answer song called "Paul Vane or Lorena's Reply
," which is essentially more of the same. "Lorena" has been used as incidental music in at least two films, and is the subject of a full length book, the 1962 treatise The Sweetheart Of The Civil War: The True Story Of "Lorena"
, which was written by Ernest K. Emurian. (thanks, Alexander Baron - London, England, for all above)