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This is probably about insanity, something the band was quite familiar with. Ex-singer/guitarist Syd Barrett's experiments with hallucinogens caused his unfortunate fall in the late '60s.
Many people consider this and "Eclipse" one song because they run seamlessly together at the end of the monumental album, Dark Side Of The Moon. Radio stations usually play them together. (thanks, Matt - Russell Springs, KY, for above 2)
The line, "You raise the blade, you make the change" is a reference to frontal lobotomies. (thanks, Eoon - Brisbane, Australia)
The line, "And if the band you're in starts playing different tunes" is a specific reference to Syd Barrett's propensity for playing the wrong song on stage during his "episodes" towards his final days with Pink Floyd, which subsequently led to his dismissal.
Many people believe that Dark Side Of The Moon synchs up with the movie The Wizard Of Oz (beginning the record just as the third roar from MGM lion is displayed). This song plays while the scarecrow sings "If I only had a brain." (thanks, Ash - Discovery Bay, CA)
The lyrics, "The lunatic is on the grass" do not refer to the drug marijuana, but rather actual sod. Roger Waters based the line on the signs that state "Stay Off The Grass" and how he thought anyone who disobeyed the signs was crazy. The line, "Got to keep the loonies on the path" supports this, meaning that people must not get off the path and onto the grass. (thanks, Connor - Stonington, CT)
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