This was the first song to crossover from the R&B charts to the mostly white pop charts of the day. Like several other songs previously heard exclusively in black bars or nightclubs, it was covered by the crooning Pat Boone. Concerned about how educated, upper-class whites would respond to the title, he originally wanted it changed to "Isn't That a Shame," but the producers realized the original title would sell better and kept it.
Boone's cover was a huge hit, going to #1 on the US Pop charts and reaching #7 in the UK. This gave Domino's original recording a boost, and helped it cross over.
According to Boone, both Domino and Little Richard (another artist he covered) appreciated his efforts. In an interview with Songfacts
, he said: "When I recorded their songs, my records of their songs sold 10 times that - and introduced them to the white audiences, or the pop audiences. So, they were grateful for my having recorded their songs. And of course, we became friends, as well."