With the line, "Everybody Must Get Stoned," this song is often associated with smoking marijuana, although Dylan insists it isn't, stating, "I have never and never will write a 'drug song.'" It is more likely about trials of relationships with women, and Dylan has hinted that it could have a Biblical meaning. Answering a question about people interpreting this song to be about getting high, Dylan told Rolling Stone
in 2012: "These are people that aren't familiar with the Book of Acts."
The Book of Acts is from the Gospel of Luke, and contains an account of a stoning: "Stephen, full of the Holy Spirit, looked up to heaven and saw the glory of God, and Jesus standing at the right hand of God... And when they had driven him out of the city, they began stoning him, and the witnesses laid aside their robes at the feet of a young man named Saul."
In this story, Stephen received his sentence after giving a speech to authorities who were going to kill him no matter what he said. This relates to how Dylan felt about his critics, who were going to figuratively "stone" him no matter what he did. (More on the meaning of "stoned" in popular songs