Cooper told the story of the song in an interview with Classic Rock Revisited
: "Bob and I learned a long time ago that when you start writing a song, and it starts developing it's own personality; you just have to let it be what it is. You can't try to force a round peg in a square hole. Just write the song, see what it ends up being and then see if it works. You can't start trying to twist it into what you want it to be. Bob and I started writing this song, "Last Man On Earth" and it ended up being a Tom Waits song – I sing it somewhere between Tom Waits and Jimmy Durante. When I saw Tom at the Hall of Fame I said, 'Tom, this is going to sound weird, but I've always been a big fan of yours. I have written a new song that, coincidentally, is a tip of the hat to you. When you hear it, you will know which song I am talking about.'
That song really ended up coming out well and it really fit the story line well. It reminds of that old Twilight Zone
with Burgess Meredith where he ends up in the basement because of an atomic explosion. When he finally goes upstairs, he's now got all of the books in the world but he then breaks his glasses and now he can't read them. That was kind of this idea. Alice is the last man on earth. He can stink, he can swear and he can do anything he wants to do because there is no one there to tell him 'yes' or 'no'."