A track from David Byrne's 2001 album Look into the Eyeball, the song was also featured on the former Talking Heads frontman's 2007 Live from Austin, Texas LP and DVD. On the latter, Byrne explains that the lyrics are about trying to love human beings by taking a "Martian's perspective" on humanity and trying to accept them despite failings for what they are.
This was released as the lead single from Look into the Eyeball. The radio edit of the song omits the line referring to cannabis.
The song was selected by Microsoft as the sample music for Windows XP to demonstrate the new Windows Media Player. Byrne recalled to Uncut Aug 2015: "Their new operating system included an audio/video player and they used a song I'd done as a demo of how their audio player worked – so that when you opened up the player there was something in there already. I thought, 'This will be a clever way to get a song from my new record to millions of people, to create awareness of the new recording. It didn't really have that effect."
"Here Comes Your Man" is the closest the Pixies came to a hit in America. It was rumored to be about a drug dealer, but Black Francis says it's just a story about some hobos who travel by train and die in an earthquake.
Until December 5, 1998, a song had to be issued as a single to make the Hot 100. Aaliyah's "Try Again" was the first tune to top the chart based on airplay alone, without any sales figures being included.