In this song, Drake references a female he deeply trusts, and as result has made her his go-to-girl. The song was released following "Charged Up" and "Hotline Bling" as part of the weekly mix for his Beats 1 Radio show OVO Sound.
The expression right hand man or woman refers to an invaluable or chief assistant, who provides help in daily business or personal tasks. It comes from the fact that a person's "right hand" is their most trusted and loyal helper.
Some right hand fun facts:
Around 90% of the world's population is right-handed, a percentage that has remained steady for the last 30,000 years.
There were more left-handed people with IQs over 140 than right-handed people. Albert Einstein, Isaac Newton, Charles Darwin, and Benjamin Franklin were all lefties.
Studies have shown that right-handed people tend to scratch with the left hand and left-handed people with the right.
Female cats tend to be right-pawed; tom cats tend to be left-pawed.