Drake's parents divorced when he was five years old, after which his mom, Jewish Canadian educator Sandi Graham, raised him in Toronto. This maternal ode recounts various conversations between the rapper and his mother, who still plays an important role in his life. Drake gives joint credit to his mom and Toronto for helping him cope with all of the issues he had growing up and enabling him to become the man that he is today.
The titular '6' is Drake's nickname for Toronto. It is thought to be derived from the city's area codes, which both feature the number six (416 and 647).