In this song, Tunstall swats away the gnats of confusion that impair her ability to succeed - the little annoyances and moments of self-doubt that can cripple the most ambitious of us. Tunstall realizes that controlling these moments is the key to controlling her life.
This is one of several KT Tunstall songs that has appeared on the TV show Grey's Anatomy. Along with extensive touring, this exposure helped make Tunstall an international hit.
"It's the End of the World As We Know It (And I Feel Fine)" was inspired by a dream where Michael Stipe conjured up images of people with the initials L.B.: Lester Bangs, Leonid Breshnev, Lenny Bruce and Leonard Bernstein.