This song about marijuana originally showed up in a "Monstervision" video, The Adventures of Mary Jane Holland
, which Gaga posted to YouTube on August 19, 2013.
The usage of Mary Jane as a slang term for marijuana is an obvious one given their similarities. The word marijuana itself derives from the Mexican Spanish word for the drug, marihuana
. Other Pop artists who have used the phrase as a song title in a weed context include Tom Petty and the Heartbreakers
, Rick James
and probably The Association