Frontman Nathan Leone explained this song to Kerrang! magazine April 4, 2009: "This is about panic attacks. We all get them and I get them a lot! It feels like your mind is going to slip, it's terrifying and they are horrific. You feel like you are going insane. I think our band lifestyle has made them worse, but I've had them my whole life. I used to throw up after playing soccer from sheer panic. It's just nerves and anxiety. It's the weirdest thing."
The line in John Mellencamp's "Cherry Bomb" that sounds like "that's when a smoke was a smoke" is actually "that's when a sport was a sport," according to the published lyric. In that sense, "sport" is an endearment for someone of good nature.