Like the other tracks on Journal For Plague Lovers, this song originated from a folder containing lyrics, which the Welsh band's former guitarist Edwards handed to bassist Nicky Wire, shortly before disappearing in early 1995. Vocalist James Dean Bradfield told the NME May 16, 2009: "This song did feel like a dead flower to me, because it's got the possibility of just giving up on conjugal relationships or love. And that emotion is not turned to anybody in particular except himself. It's just saying, 'Perhaps I'm not worthy of love, or love in relationships doesn't work for me."
Bassist Nicky Wire commented to the NME: "I just thought it was another one that seemed to come to a conclusion after a process. 'I endeavoured/ To find a place where I became untethered.,' it just feels like he's looked at the possibilities and a lot of the conclusions aren't pretty or positive, but they are…rational. It's just nice to know, I think, well, I know for a fact from the last 10 days that we were with him, that he'd reached a place where he was much…not happier."
Angus Young created the distinctive opening guitar part for "Thuderstruck" by playing with all the strings taped up, except the B. He learned the studio trick from his older brother George Young, who was the rhythm guitarist for The Easybeats.