This was the first single to be released from Venomous Rat Regeneration Vendor, the fifth solo studio album by former White Zombie frontman Rob Zombie. It was the first Rob Zombie album to feature drummer Ginger Fish who, with guitarist John 5, was part of Marilyn Manson's band.
Asked what the story is behind the album's title, Rob told Revolver magazine: "There's no real story behind it. I just thought of it one day. With every album I've ever made, we'll get it basically one hundred percent done and everyone will go, 'OK, what's the title?' And I'm like, 'I don't know what the fu--in' title is yet. It hasn't hit me.' And then one day I'll just blurt out, 'La Sexorcisto: Devil Music, Vol. 1!' or 'Hellbilly Deluxe!' It's the same with this one. I have it written down somewhere, but I don't remember doing it."
It was never a big hit, but "She's A Rainbow" became one of the most popular Rolling Stones songs in the digital age when it started showing up in commercials (iMac, Photoshop), and TV shows (American Horror Story: Coven, Ted Lasso).