In this song Cabrera offers his best to his former sweetheart, Ashlee Simpson. He explained: "A lot of times, when people break up, they're all pissed off at the other person. They wish the worst for them. But this song is kind of the opposite - it's like, we're not together, but God made you to shine on. You do your thing, I'll do my thing, and hopefully everybody will be doing well."
"Here Comes Your Man" is the closest the Pixies came to a hit in America. It was rumored to be about a drug dealer, but Black Francis says it's just a story about some hobos who travel by train and die in an earthquake.