Guitarist Brace Paine explained to Spin magazine: "The end of the world is supposed to happen on December 21, 2012 - there's supposed to be some massive collision with an asteroid. The song is a sort of a nod to that concept. You know, I heard Lil Wayne is having a 2012 party."
Vocalist Beth Ditto (from the NME June 27, 2009): "It's about how we think we're invincible but we're not. We treat life like we're invincible, but actually we're really vulnerable - especially to each other."