This '70s-styled powerpop/glam-rager finds vocalist Jeff Tweedy singing of love and devotion. He told Mojo magazine: "It's one of those songs that, as you listen to it, the heels on your shoes start growing and the bottom of your pants start to flare."
The song explores Tweedy's long-lasting marriage to his wife Sue. He told UK newspaper The Sun: "I think an obsession with romantic love in a relationship causes a lot of pain.I think the only real hope for any relationship, in terms of longevity, is to maintain the ability to fall in love with each other and not get too distracted when it's not too perfect. Me and my wife have been together for 20 years and I think it's pretty unrealistic to always be in love."
The Darren Romanelli-directed animated video finds the Wilco band members in cartoon form performing the song alongside Popeye, Olive Oyl, and co. The Chicago rockers previously appeared in a Popeye strip that appeared on January 22, 2012. That cartoon shows Popeye and his crew helping Wilco in handing out cans of Wilco Spinach to the crowds on the dockside.
Two tears roll down Sinead O'Connor's face. toward the end of the video for "Nothing Compares 2 U." They were shed because she associated the song's lyrics of love and loss with her mother, who was killed in a car accident in 1985.