"Handle With Care" started as a George Harrison song with guest appearances by Roy Orbison, Bob Dylan, Tom Petty and Jeff Lynne, but it went so well the five of them decided to form a group - The Traveling Wilburys - and record an entire album.
Alicia Keys got a huge break when Oprah had her perform her debut single, "Fallin'," on her show.
Neil Young rarely allows his songs to be sampled, but he let the Canadian group Redlight King use "Old Man" in their 2011 song, also called "Old Man."
"Toxic" was the most-searched song on Google in 2004 and helped Spears become the most-searched artist that year, a title she held from 1999-2001.
When Marc Cohn played "True Companion" to his girlfriend, she thought he was proposing. He wasn't, but he did eventually marry her.
"Jessie's Girl" was the #1 song in America when MTV went on the air. They put it in hot rotation right away, making the song even more popular.
The lead singer on "Da Doo Ron Ron" and "Then He Kissed Me," La La explains how and why Phil Spector replaced The Crystals with Darlene Love on "He's A Rebel."
What happens when Kurt Cobain, Iron Maiden and Johnny Lydon are told to lip-synch? Some hilarious "performances."
Collaborating with T Bone Burnett, Leslie Phillips changed her name and left her Christian label behind - Robert Plant, who recorded one of her songs on Raising Sand, is a fan.
The (Meat)puppetmaster takes us through songs like "Lake Of Fire" and "Backwater," and talks about performing with Kurt Cobain on MTV Unplugged.
With his X-wife Exene, John fronts the band X and writes their songs.
Deep Purple's guitarist since 1994, Steve talks about writing songs with the band and how he puts his own spin on "Smoke On The Water."