This song is a tribute to Johnny and June Cash and the enduring love they had for each other. Newfield adds that she desires to have a similar relationship with her lover. The former Trick Pony vocalist became close to the couple during the last five years of their lives.
In the song's music video, Newfield sings the chorus dressed in black, surrounded by flames. This is a reference to the Johnny Cash song "Ring Of Fire."
Mike Campbell from Tom Petty & the Heartbreakers played the slide guitar on "Sixth Avenue Heartache." There is a connection here - Wallflowers lead singer Jakob's dad, Bob Dylan, played with Tom Petty in The Traveling Wilburys.