This is the first single from the Courtney Love-fronted Alternative Rock band Hole's fourth album, Nobody's Daughter and their first new single for ten years. It is the first release of the new lineup of Hole, which apart from Love also includes British guitarist Micko Larkin (formerly of London indie rockers Larrikin Love), bassist Shawn Dailey (of Rock Kills Kid), and drummer Stu Fisher. Jack Irons, formerly of the Red Hot Chili Peppers and Pearl Jam, also played drums on Nobody's Daughter.
The song was first played live during Hole's reunion show at the Shockwaves NME Awards show at London's O2 Shepherds Bush Empire on February 17, 2010. It had its radio premiere on New York station, WRXP on March 3, 2010.
Love penned the song with Hole guitarist Micko Larkin. She told MTV News why she feels the subject matter strikes a chord. "It just felt zeitgeist. It just felt right," Love said. "There are so many skinny little bitches doing so many bad things. It was like, remember when Paris Hilton used to say 'That's hot?' ... It was just the right phrase for the right time."
Love told MTV News the titular "Bitch" doesn't actually exist. "We haven't found her yet," she said, with a laugh. "A lot of reviews have focused on whether the 'Skinny Little Bitch' is me, except I've only become skinny [in my 40s]. I only figured out how - when I'm stressed, instead of overeating, under-eating - in my 40s. And I've never been little. I'm 5'11"; there's a lot of me. So I'm not really skinny, nor am I little. I might be a bitch though."