The "Sad City Sisters" are ladies of ill repute Jethro Tull leader Ian Anderson encountered during his tenure as a rock star. Anderson had little interest in these indulgences and looked at them with a critical eye. He explained: "Sad City Sisters throws up memories of a Saturday night in Cardiff, Wales when I was on my way home from our concert in St David's Hall some years ago. It could equally well have been any town in the UK, I suppose, or even most cities of the Western World. What possesses hell-bent and vulnerable young people to slip so easily into that tragic loss of dignity and end up sprawling drunk in a wet and windy street at midnight?"
This was the second single from The Zealot Gene, the first Jethro Tull album since 2003, although Anderson put out solo albums in the interim. "Sad City Sisters" came with a video directed by Sam Chegini that portrays the subject of the song as a puppet being passed around and manipulated.
Ariana Grande's collaboration with Zedd, "Break Free" came about after the Russian-German producer overheard Grande performing at a label showcase while he was backstage, and he mentioned to his team that he wanted to work with her.