Gaga explained to E! News that this track from her Born This Way Special Edition album is about how when she moved to downtown New York at the age of nineteen, she was introduced to an entirely new way of thinking that was so different from the way she was taught. Up till then, iconic imagery had taught her entire life to look at Jesus and religion a certain way. Black Jesus represents an entirely new way of thinking to her, ("Jesus is the new black"), which she believed was caused by meeting new people and seeing new things.She added that the Amen Fashion part of the song concerns how having a new way of seeing is as easy as changing your fashion.
According to Gaga, the two phrases that make up the title are interchangeable. She had used both phrases in the song, liked them equally, so she decided to use both.
In a post on her Facebook wall, Lady Gaga explained: "Black Jesus was Justin Timberlake's favorite. Its about how putting on a new spirit is as easy as putting on fashion. Amen."