Vocalist Robb Flynn wrote this song whilst the band's main songwriter, guitarist Phil Demmel, took some time out in 2010 to deal with some personal stuff. Demmel told Sonic Excess magazine: "You know, he had all this music pouring out of him, and he had to get it out…"
The song features a chorus of children singing in the intro. The kids concerned belong to Phil Demmel, Robb Flynn and studio engineer Juan Urteaga.
Angus Young created the distinctive opening guitar part for "Thuderstruck" by playing with all the strings taped up, except the B. He learned the studio trick from his older brother George Young, who was the rhythm guitarist for The Easybeats.