Asked about his inspiration for the song during a Reddit AMA, DeVaughn replied: "I was in the studio in an environment for days where everyone but me was using hard drugs. Left to write by myself with the engineer I made the best of it. 'You as pure as snow from columbia...' lol. I know crazy right."
Two tears roll down Sinead O'Connor's face. toward the end of the video for "Nothing Compares 2 U." They were shed because she associated the song's lyrics of love and loss with her mother, who was killed in a car accident in 1985.