Brett Anderson explained in a press release that this, "is a bittersweet, bouncy pop song with a whole load of choruses stuck together."
Regarding the song's meaning, Anderson said: "It's about infatuation and attraction and the fever of falling head first back into the pit."
This was released as the first single from Suede's sixth album, Bloodsports. Brett Anderson explained the album title to NME: "It was supposed to be about the fight and the chase and the struggle of relationships, really. The initial idea of the album was that it would be ten songs charting the stages of a relationship from meeting someone to it crumbling and splitting up. There's a book I really like called Essays in Love by Alain de Botton, which it was inspired by. But that fell apart a little bit."
Bassist Mat Osman described the song to Q magazine as, "like a load of choruses put together."
This song almost became the album title, Brett Anderson explained to NME: "'It Starts And Ends With You' sort of summed up the cyclical nature of what I wanted the album to be about, sort of like, you know, the circle of a relationship. But I felt as though it was a little bit too ... kind of long-winded to be a title, so I changed it to Bloodsports."