This song is written by the legendary songwriting team of Jerry Leiber and Mike Stoller, and was released as the B-side of The Coasters' hit "Searchin'." The Coasters were a spin-off from an earlier group The Robins, with the members Carl Gardner and Bobby Nunn. To this duo, they added Billy Guy and Leon Hughes and became The Coasters. The group had one final re-arrangement a few years later to reach the classic lineup of Carl Gardner, Billy Guy, Cornell Gunter, and Will "Dub" Jones. Their manager was none other than Lester Sill, Leiber and Stoller's longtime mentor.
Jerry Leiber tells the story of how "Young Blood" was written, in the book Hound Dog: The Leiber & Stoller Autobiography
. He was on his way to dinner with the family of Atlantic Records executive Jerry Wexler, when Jerry gave him a challenge. Wexler sprung the title "Young Blood" on Leiber while they were driving to Wexler's home, and asked him if he could write lyrics to go with it. Leiber asked "How far are we from your house?" and when Wexler told him it was fifteen minutes, Leiber responded "I'll have the lyrics finished before we get there." And he did!