The central theme of the song is about the tension between the temptations of selling your soul to the Devil to gain fame and riches and trying to maintain a clean soul. A$AP Rocky is open about his use of illegal drugs such as LSD and sleeping around with women, but he still maintains a relationship with God. He said during an interview with Sway in the Morning: "I pray everyday to God. I pray over cookies before I eat 'em. I'm thankful for blessings, and I talk to God everyday."

London newcomer Joe Fox croons the hook over Danger Mouse's psychedelic production. He recalled to Fader: "I had that 'Holy Ghost, I'm on my knees hook.' Rocky wrote the entire rap for that in one night. He just put it down. I think if things are meant to happen, then they just happen quite quickly and organically. It was never a struggle."