On this song Harris shares vocals with rapper Izza Kizza from Timbaland's Mosley Music stable.
The song's prominent use of acoustic guitars may have surprised fans of the electronica musician. However in interviews Harris has expressed his displeasure with his previous release, his more hardcore dance record I Created Disco, claiming he didn't work hard on it and cut too many corners. He said in publicity materials of Ready For The Weekend: "I wanted to make something I would be proud of: 'This is as good as I can do'. So I don't just have that one album to my name that I'm not particularly pleased with."
Lily Allen wrote "Something's Not Right" for the soundtrack of the Peter Pan prequel, Pan. The song was inspired by the heartache that Allen experienced after suffering a miscarriage when she was six months pregnant with her first child by husband Sam Cooper in 2010.