Songfacts®:

• In this track, which features hospital sound effects, Dr. Wayne rhymes about healing struggling rappers who are "sick" and need saving.
• This was produced by the rap producer Swiss Beatz. He told Rhapsody that Jay Z who, like Lil Wayne has the real life surname of Carter, considered recording this track first. He explained: "It was a concept that could have either been for Wayne or Jay. All he had to do was fill in the blanks. It had 'Good morning, Dr. Carter,' the breathing and the heartbeat. Jay heard it first and loved it. But I didn't expect him to take it once I seen where he was going with [American Gangster]. It just wasn't good timing. It definitely fit Wayne. He's representing the next generation and he delivered on it. The crazy part is when Jay was talking about the concept, he was talking about rebirthing a new artist, and whoever the new artist was would have been the feature. That probably was going to be Wayne, and Wayne wanted to feature [Jay] on it. So they were thinking the same thing without knowing it."
• This samples "Holy Thursday" by David Axelrod, which originally appeared on the American composer's 1968 William Blake inspired album, Song of Innocence. "Holy Tuesday" is also included in the soundtrack for the video game Grand Theft Auto IV.