Songfacts®:

• This third single from American rapper Lil Wayne's seventh studio album Rebirth was produced by Miami production duo Cool & Dre. Cool explained the song's lyrical content to MTV News: "He's talking about a chick that's on fire. He's on his knees praying to the Lord to keep him clear because she's on fire. He's got a bad one! She's that bad that's she might have came straight outta hell."
• The song borrows from American pop rock singer Amy Holland's "She's on Fire" from Giorgio Moroder's soundtrack for the 1983 movie, Scarface. Dre discussed the sample with MTV News: "If you speak to Wayne, Wayne will tell you the reason why he loves the record is he gets to do everything on the record. He gets to spit on the record, he gets to sing on the record, he gets to play the guitar on the record. One night I was watching Scarface, and I woke up in the morning, had the damn 'She's on Fire' in my head. I called up Cool, like, 'Yo, we gotta flip this.' The way the sample was, you couldn't flip it. It's like a disco song, but you hear the guitars. I was like, 'We should put this sh-- on steroids and turn it all the way up. Throw some 808s on it and really crank this sh-- up.' We redid the whole beat and kept the 'she's on fire' [vocal sample]. We gave it to Wayne. Wayne is the Fireman, so it's perfect. But we heard it after he did it - we didn't know he was gonna kill the guitar like he did."
• Wayne plays the guitar on this track. Dre told MTV News: "It's never us producing a beat for Wayne. It's a collaboration. It's always a collaboration. It's not like, 'OK, make a beat.' We're making the music with him in mind and the sh-- he does, [thinking,] 'He'll probably rap; make the music change here.' When we gave him the Pro Tools, he goes in and he amplifies the beat. That song has drops all over it where hits the guitar. Music is so f---ing boring right now. It's good to wake muthaf---as up. Wayne sings on it, he spits on it, and he plays the guitar on it. He gives you everything on one record where his mind is at right now."