This was produced by Jermaine Dupri. Carey told Base magazine about working with the R&B producer: "What I usually do is go to Atlanta to work with Jermaine, we write the song, then I take it and leave and do my vocals. Then we work on the mix together afterwards-that's how I work with everybody."
Carey: "'Thanx 4 Nothin' was the first ballad I wrote for this album, this song is gonna resonate with people who are really going through like a bleak moment in their relationship, where it's like 'Yeah... fantastic. Thanks for nothing.' Like, you know what that is. I'm being really sarcastic. It's a sarcastic moment in the land of 'Mariah Carey songs'. People listen to the song when Jermaine says in the beginning 'this is for all the women who are sick and tired of being played.' He knows it. [laughs] That's what it is."
The TV show Cheers was nearly canceled after its first season, but the theme song, "Where Everybody Knows Your Name," was very popular. To satisfy viewer demand, the theme was made into a full song and released as a single.