This is about Lorenzo Odone, the severely disabled young boy from the 1993 film Lorenzo's Oil. Lorenzo's mother Michela had been working with Lorenzo on putting his life story into lyrical form as part of his stimulation, and it was Lorenzo's wish that Collins sing the song. Michela Odone received a songwriter credit along with Collins.
As of 2005, Lorenzo was still alive. He is severely disabled and cannot speak. He communicates through blinking his eyes to say no and wiggling his fingers to say yes.
Suggestion credit: lauren - Bensalem, PA, for above 2