This song confronts economic inequality in America. Prophets of Rage guitarist Tom Morello explained: "The 110 is a freeway in Los Angeles and living beneath it are thousands of homeless people. Bentleys and Rolls Royces roaring by are literally driving on top of the poor and their makeshift homes, a picture-perfect analogy for the grotesque economic inequality that plagues our times."
John Lennon's lead guitar work on Yoko Ono's "Walking On Thin Ice" proved to be his final creative act. It was upon their return home after completing laying down the track that Lennon was murdered by Mark David Chapman.