Tinashe explained the song's meaning to The Idolator
: "We are trying to kill 'turnt up,' 'turned up on life,' 'YOLO,' all that stuff," she said. "And we are trying to bring in '2 On.' So basically, it just means super hyped up, super extra out on whatever emotion that it is if you are super, super happy, then you are '2 On.' You got it?"