For Eminem, the titular "best friend" is the late Detroit rapper Proof, who was fatally shot in a night club on April 11, 2006.Who you think I'm talking bout?
Lifts me up when I'm down and out,
Still look to him without a doubt, still got a best friend
Proof was one of Eminem' closest pals and the rapper has paid tribute to his fallen friend on a number of previous tracks including Relapse's "Déjà Vu
" and Recovery's "You're Never Over