Mark Schultz wrote this song about a family dealing with their son's cancer when he was a youth minister at a church in Nashville, Tennessee. It was inspired by the grieving of a couple in his church, whose son had been diagnosed with leukemia. Shultz observed the struggles of the mother and father. He explained in CCM Top 100 Greatest Songs In Christian Music: "Louise often stayed up with (Martin) until he fell asleep. She would rub his back and try to comfort him, but she felt helpless. Some nights, John would wake up and walk down the hall to Martin's room and watch him sleep. As he stood there, he would try to imagine what life would be like without his son."
Schultz added that he "tried for several months to write a song for John and Louise, but nothing seemed to capture what they were going through. I couldn't begin to understand the depth of pain John and Louise faced every day - but God did." He then went on to explain that eventually "the only thing I had to do with this song is that I just happened to be there when God sat it in my lap."
In 2001 the Leukaemia and Lymphoma Society gave Schultz the Beacon Award for his awareness-raising efforts.
Ken Kern from Broken Arrow OkGod laid this song in my lap after my son had a tragic motorcycle accident that left him in a coma for weeks. I watched as my wife held his hand and laid her head on his bed and prayed. During those difficult times, I totally related with the lyrics of this song. God heard our prayers and performed miraculous work through doctors, nurses and therapists of all kinds. This song holds a special place in our hearts.