Mike Campbell from Tom Petty & the Heartbreakers played the slide guitar on "Sixth Avenue Heartache." There is a connection here - Wallflowers lead singer Jakob's dad, Bob Dylan, played with Tom Petty in The Traveling Wilburys.
In Gary Numan's "Cars," the message is that cars lead to a mechanical society devoid of personal interaction. This didn't stop automakers from using it in commercials. Both Nissan and Oldsmobile have used it in ads.