"Piano Man" was inspired by Billy Joel's time playing at a piano bar in Los Angeles. The "real estate novelist" was a guy who always talked about writing a book, but spent all his spare time in the bar.
David Bowie's "Space Oddity" tells the story of an astronaut who cuts off communication and floats into space. The BBC used it extensively in their coverage of the 1969 moon landing - an odd choice considering the lyrics.
The Isley Brother's song, "Contagious," peaked at #19 on the Billboard Hot 100. This meant that the band of brothers became the first group to score a Top 50 hit in six consecutive decades on the chart.